Hepper blog

Search our database of over 9,984 posts with up-to-date information from our experts and veterinarians.

Hepper is reader-supported. When you buy via links on our site, we may earn an affiliate commission at no cost to you. Learn more.

Gabapentin for Cats (Vet Answer): FAQs, Uses, Dosage & Side Effects

Written and fact-checked by Dr. Chantal VilleneuveVet Approved
Dr. Chantal Villeneuve
Reviewed & Fact-Checked byDr. Chantal VilleneuveVeterinarian
Dr. Chantal is passionate about the human-animal bond and improving animals' lives through their connections with their human companions. She has worked with many different species, big and small, including dogs, cats, birds, rabbits, guinea pigs, reptiles, amphibians, and even horses and mice. Chantal is excited to share her knowledge using her writing to help people connect with their animal friends.View authorThe information is current and up-to-date in accordance with the latest veterinarian research. Read about our vets
Share
Ask us a question in the comments
person gives a pill to a cat

Gabapentin is a central nervous system medication used to manage pain, anxiety, or seizures. It was originally formulated as a treatment for seizures in humans, but it is very effective for pain relief and anxiety in animals. It can make cats slightly drowsy and uncoordinated but has few side effects, especially compared to other pain-relief medications.

What Is Gabapentin?

Gabapentin is an off-label drug. While it was made for humans, many veterinarians will prescribe human tablets or capsules for cats, and it is considered a safe medication for them.

The most common brand name is Neurontin, others include:

  • Progresse
  • Equipax
  • Gaborone
  • Aclonium
  • Gralise
  • Gantin
  • Neurostil

Because it is given off-label, it is extra important to follow your veterinarian’s prescription and not the label on the box. And do not give gabapentin to your cat without a prescription—some forms of human gabapentin contain xylitol which is toxic to cats.

Gabapentin has three primary uses: pain relief, anxiety, or seizures.

  • Pain relief: Gabapentin is used as long-term pain relief for chronic conditions such as arthritis. It is also used with other medications to manage pain after surgery or an injury.
  • Anxiety treatment: Gabapentin is used for stressful events. For example, if given 2–3 hours before a vet visit, gabapentin can help keep a cat calm during the visit, and its effects quickly fall off after 8-12 hours, so they are quickly back to normal.
  • Seizure control: Gabapentin is used long-term to manage recurring seizures. Other medications are used to stop active seizures, but gabapentin is used to help prevent seizures from happening in the first place. It is used in conjunction with other anti-seizure medications as part of a daily long-term treatment plan.
person petting a sick cat
Image By: Alexander Andrews, Unsplash

How Is Gabapentin Given?

Gabapentin is usually given every 8–12 hours, depending on the condition being treated.

The amount given will vary depending on three important things:

  1. The size of your cat: Your vet will calculate the dose according to your cat's weight.
  2. The condition being treated: Pain, seizures, and anxiety all need different levels of medication to be effective.
  3. How your cat responds: Especially when treating seizures or anxiety, instead of starting at the highest dose and hoping for the best, many vets will start with a low dose and slowly, incrementally, increase the dosage depending on how your cat responds.

What Happens if You Miss a Dose?

This depends on why your cat was given gabapentin in the first place. If you miss a dose, consult with your vet, they will most likely say to give the next dose as normal. Do not give more next time.

  • If the gabapentin is treating chronic pain—arthritis, for example—a cat will probably just be a little stiffer until their next dose. But if it is after surgery, the consequences of that pain can be significant. A cat that misses a dose of pain relief is more likely to chew, scratch, or cause injury to its surgical site. They are also more likely to become severely stressed, to not eat or drink, or to injure themselves in some other way. Either way, a cat in pain will take longer to heal after surgery or injury.
  • For anxiety, if gabapentin is not given before a vet visit, or as more often happens, it's given fifteen minutes before the appointment instead of two hours beforehand, then you're probably going to have to reschedule your visit because the medication has not had enough time to take effect.
  • If you miss a dose, your cat is more likely to have a seizure. Seizure treatment tries to maintain a steady state of medication in the body because ups and downs of medication concentration in the body can trigger seizures.
vet holding a senior cat
Image By: Alice Rodnova, Shutterstock

Potential Side Effects of Gabapentin

The beauty of gabapentin is that it has very few side effects. The only real side effect is some level of sedation, which can vary from drowsiness to being unsteady on their feet to just taking a few extra naps.

Frequently Asked Questions (FAQs)

Can I give gabapentin with food?

Technically, it can be given with or without food; the medication is not affected either way.

But it does not taste very good, so it often must be hidden in treats or coaxed down.

It is tempting to hide the pills in a bowl of food, but cats are sneaky and are very good at hiding the fact that they did not eat their medication. So, usually, giving it in their absolute favorite treat right before a meal—when they are hungriest—works best. That way you can watch them swallow the whole thing.

Getting your cat to swallow the medication is probably the worst thing about gabapentin.

maine coon cat eating
Image By: Lita Keire, Shutterstock

Why am I giving my cat so many pills for pain?

Gabapentin is used to relieve pain because it does not have many side effects, but it is probably not enough to manage severe pain alone. Opioids, for example, are the best at relieving pain, and NSAIDs are great for reducing inflammation, but both can have some negative side effects.

Gabapentin does not have these side effects, but it does not block pain as effectively as most opioids and does not reduce inflammation like NSAIDs. So, in cases of severe pain, gabapentin is often used in combination with other pain meds so that a smaller dose of opioids and NSAIDs can be used, but more pain relief is achieved.

In fact, using more than one type of pain relief is considered safer and more effective than relying on just one type. This type of medication is called multimodal analgesia (pain relief). It uses more than one medication so that multiple points along the pain pathway are blocked, so pain relief is increased while the amount and side effects of individual medications are reduced.

Why am I giving my cat so many pills for seizures?

There are numerous medications used for controlling seizures, and while gabapentin can be helpful, it is probably not the most effective, especially if it is used alone. In other words, other drugs are more effective at treating seizures, but when gabapentin is added on top of these together, they can become even more effective than when used alone.

Long-term seizure control includes daily medicating and carefully titrating medications for each individual. Slowly increase the doses of each drug until the best control is reached while keeping the side effects of the medications used to a minimum.

Conclusion

Not much is more complicated than treating problems in the nervous system, such as pain, seizures, and anxiety. Gabapentin is one of the many medications veterinarians use, often in combination with other medications, to manage these complex conditions. Communicating with your vet and carefully watching your cat’s response to medication will help everyone find the dose that works best for your cat. Do not stop giving gabapentin without discussing it with your vet.

Just like any medication, gabapentin can have side effects, particularly at high doses as it can cause drowsiness and incoordination. The dose prescribed will depend on your cat’s medical condition, body condition, how they respond to the medication, and other medications used at the same time.

See Also: 

Sources
  • Ramsey, I. (2008). BSAVA small animal formulary (No. Ed. 6). British Small Animal Veterinary Association.

  • The Merck Veterinary Manual. Whitehouse Station, NJ: Merck & Co., Inc. 2023


Featured Image Credit: Piskova Photo, Shutterstock

Get Hepper In Your Inbox

Pet care tips from our vets and experts, straight to your inbox.

List

Select all that apply.

You may opt-out at any time. View our Privacy Policy for more information.

Dr. Chantal Villeneuve
Authored by

Dr. Chantal Villeneuve

Join the conversation

Ask a question, share your story, or send private feedback.

Rate this post
Required to post. Only our editors see your rating.
Who should see this?

A human reviews every comment before it appears. Your email is never published.

Picked to go with this article

Gabapentin for Dogs: Uses, Dosage & Side Effects (Vet Answer)

Gabapentin for Dogs: Uses, Dosage & Side Effects (Vet Answer)

Few things make pet owners feel more helpless than seeing their pets in pain and suffering. You want to help them feel better, but you may not know how to. Gab…

Dr. Iulia Mihai
By Dr. Iulia Mihai ·
Amitriptyline for Cats: Our Vet Explains Usage, Safety & FAQ

Amitriptyline for Cats: Our Vet Explains Usage, Safety & FAQ

Amitriptyline is a tricyclic antidepressant that is prescribed in veterinary medicine to treat behavioral disorders in cats and dogs. Amitriptyline works by bl…

Dr. Emma Chandley
By Dr. Emma Chandley ·
How Much CBD Oil Should You Give a Cat? Vet-Reviewed Dosing Chart & Safety Guide

How Much CBD Oil Should You Give a Cat? Vet-Reviewed Dosing Chart & Safety Guide

Among humans, the use of CBD as an alternative to traditional medications has grown extensively in popularity. Many pet owners have also begun to explore using…

Elizabeth Gray
By Elizabeth Gray ·
Aspirin for Cats with Arthritis: Important Precautions (Vet Answer)

Aspirin for Cats with Arthritis: Important Precautions (Vet Answer)

The advancement of medicine and healthcare for the domestic feline population has led to an overall increase in their expected lifespans. While this is general…

Dr. Meg Barnes
By Dr. Meg Barnes ·

Keep reading

More stories you might like

CBD Oil for Cats: Benefits, Risks & Considerations

If your cat has any disease, you may be attracted to an alternative treatment that is more natural and less expensive than the means offered by your veterinari…

Genevieve Dugal
By Genevieve Dugal ·
CBD Oil for Cats: Benefits, Risks & Considerations

CBD Oil for Cat Seizures & Epilepsy: Effectiveness & Tips

If you have a cat with seizures or epilepsy, you're likely looking for natural methods to control these episodes and help your cat live a fuller and healthier…

Ashley Bates
By Ashley Bates ·
CBD Oil for Cat Seizures & Epilepsy: Effectiveness & Tips

Can I Give My Cat Melatonin? Vet-Approved Facts

If you’ve ever had issues with falling or staying asleep, chances are you’ve used melatonin. It especially comes in handy when you’re traveling and experiencin…

Kathryn Copeland
By Kathryn Copeland ·
Can I Give My Cat Melatonin? Vet-Approved Facts

Do Antibiotics Make Cats Sleepy? Cat Antibiotic Side Effects & FAQs

Treating felines with antibiotics is vital for fighting off infections, but some cats handle the medications better than others. Depending on the antibiotic, c…

Oliver Jones
By Oliver Jones ·
Do Antibiotics Make Cats Sleepy? Cat Antibiotic Side Effects & FAQs

Will Catnip Help Cats That Are in Pain? What You Need to Know!

Whether you have cats in your home or simply love watching videos of these colorful four-legged felines on your phone, you know the effect catnip can have on a…

Melissa Gunter
By Melissa Gunter ·
Will Catnip Help Cats That Are in Pain? What You Need to Know!

How to Tell if Your Cat Is in Pain: Vet-Reviewed Signs & Causes

As cat owners, it’s our responsibility to keep our cats healthy and meet their needs. But sometimes, it’s hard to meet the needs of an animal that doesn’t act…

Chelsea Mortensen
By Chelsea Mortensen ·
How to Tell if Your Cat Is in Pain: Vet-Reviewed Signs & Causes

Is It Possible for a Cat to Overdose on CBD Oil? Vet-Approved Safety Guide

One of the most frequently asked questions cat owners may worry about when giving their cat CBD oil is whether their cat can overdose on too much. Yes, it is p…

Sarah Psaradelis
By Sarah Psaradelis ·
Is It Possible for a Cat to Overdose on CBD Oil? Vet-Approved Safety Guide

How Long Will It Take CBD to Work in a Cat? Vet-Verified Facts & Safety Tips

With the ever-growing popularity surrounding the health benefits of cannabinoids, it comes as no surprise that cat owners are seeking out CBD (cannabidiol) as…

Lindsey Lawson
By Lindsey Lawson ·
How Long Will It Take CBD to Work in a Cat? Vet-Verified Facts & Safety Tips